ACROFAN

First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

GWT Outdoors Partners with Umbrosa to Offer Unique, Contemporary Umbrellas for Residential and Commercial Projects

First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

Leostream’s Success is 20 Years in the Making

First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

DigitalBridge and IFM Investors Complete $11 Billion Take-Private of Switch

OMNIVISION Unveils New-Generation Global Shutter Image Sensor for Mainstream AR/VR/MR and Metaverse

First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)-- Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust US Large Cap Core AlphaDEX UCITS ETF 05.12.2022 FEXU IE00B8X9NW27 788,469.00 USD 52,391,236.60 66.447 Contacts First Trust Global Funds PLC

Arcserve Study Finds Large Organizations Not Protecting Data as IT and Work Environments Evolve

Businesses not re-evaluating disaster recovery plans and ransomware defense as remote work expands Difficulty in ensuring data compliance with country-restricted data when using cloud providers EDEN PRAIRIE, Minn.--(BUSINESS WIRE)--Arcserve, the world's most experienced provider of backup, recovery and immutable storage solutions for unified data resilience against ransomware and disasters, has announced findings from an independent global research survey of large organizations. A key result in the research survey found that 76% of US-based respondents are not re-evaluating and updating disaster recovery plans and ransomware defense as the workforce moves to a remote work model and the increased use of mobile devices on the data perimeter. As cyber criminals focus their attacks more on remote workers, it is a business imperative that organizations regularly assess changes in IT and work environments and bolster ransomware defenses and update disaster recovery plans accordingly. Additional survey insights emphasize the lack of awareness of the need for an end-to-end data protection plan. Only 56% of respondents replied that edge and remote site data protection is critically important for their data recovery solution. Cybercriminals are continuously looking for different ways to infiltrate a business, so a data backup and disaster recovery strategy is essential to ensure that all parts of an organization remain operational even after a ransomware attack. The research survey also revealed that 56% of US-based respondents found it difficult to ensure data compliance with country-restricted data (Canada, EU) when using cloud providers. As cloud computing adoption grows and country privacy and ownership laws become more restrictive and complex, global organizations will struggle to manage their data across borders. Said Florian Malecki, executive vice president of marketing at Arcserve: "Our survey has unearthed significant data vulnerability gaps in large organizations' view and approach to data protection as they standardize on a hybrid workforce strategy. Ransomware attacks continue to disrupt business operations significantly, and this issue is not going away anytime soon. It is critical that businesses continuously review and update their disaster recovery plans and incorporate data backup and recovery solutions and immutable storage as the foundation of their data resilience plan." About the research conducted by Lead to Market: IT executives of large organizations were interviewed for the survey. All participants had a budget or technical decision-making responsibility for data management, data protection, and storage solutions at a company with 500 to 5,000 employees and at least 100 TB of data. The survey was fielded in North America, the United Kingdom, and Australia. About Arcserve Arcserve, a top 5 data protection vendor and unified data resilience platform provider, offers the broadest set of best-in-class solutions to manage, protect, and recover all data workloads, from SMB to enterprise, regardless of location or complexity. Arcserve solutions eliminate complexity while bringing best-in-class, cost-effective, agile, and massively scalable data protection and certainty across all data environments. This includes on-prem, off-prem (including DRaaS, BaaS, and Cloud-to-Cloud), hyper-converged, and edge infrastructures. The company's nearly three decades of award-winning IP, plus a continuous focus on innovation, means that partners and customers, including MSPs, VARs, LARs, and end-users, are assured of the fastest route to next-generation data workloads and infrastructures. A 100% channel-centric organization, Arcserve has a presence in over 150 countries, with 19,000 channel partners helping to protect 235,000 customers' critical data assets. Explore more at arcserve.com and follow @Arcserve on Twitter. Contacts Jock Breitwieser Arcserve +1 408.800.5625 jock.breitwieser@arcserve.com

In a State Ravaged by Drug Overdoses, Spero Health Brings Lifesaving Addiction Treatment to Beckley, West Virginia

BRENTWOOD, Tenn.--(BUSINESS WIRE)--Spero Health, a national leader who has helped more than 35,000 patients on their journey to stable recovery from addiction, just announced it is opening a new clinic in Beckley, WV on December 8th. Located at 122 Professional Park, this new clinic marks the 3rd location Spero Health has opened in the state that joins a network of more than 95 Spero Health locations throughout Kentucky, Ohio, Tennessee, Indiana, Virginia. Immediate appointments are available and individuals who need addiction treatment services are encouraged to call: 866-755-4258 for more information or to schedule an appointment. Spero Health is in network with West Virginia Medicaid and most commercial insurance plans to ensure cost is not a barrier to treatment. According to the National Center for Health Statistics in 2020 alone over 100,000 Americans fatally overdosed, with West Virginia seeing the 2nd highest increase in deaths compared to all states. Provisional data for 2021 suggest that 1 American died of drug overdose every 5 minutes. Spero Health is responding to these staggering statistics by expanding addiction treatment services across states most impacted by the drug epidemic, so communities have access to lifesaving care close to home. According to the CDC from September 2020 to September 2021, West Virginia saw 1,284 overdose deaths, which was a slight decline from previous years. Speaking about this, CEO of Spero Health Steve Priest said, “Although recent data is encouraging, we can’t lose sight of how urgent the need is for our communities to have access to addiction treatment close to home, so we continue to see declines in these numbers. For the past several years, West Virginia has had the highest number of overdose deaths in the nation, and it has destroyed thousands of families. Synthetic opioids, including fentanyl, have become the most common drugs involved in drug overdose deaths in the United States. It’s an extremely dangerous substance and often gets mixed in with other drugs and users unknowingly ingest it. We are also seeing a resurgent of methamphetamine use complicating the drug epidemic further, but there is hope. Spero Health is confronting this crisis through expansion of a wide range of treatment options, so our communities have a place to turn for help. This is our third clinic in West Virginia, and it is just the beginning of our work in the state.” Spero Health strives to meet people where they are by offering a community-based approach to treatment utilizing an innovative and evidence-based integrated care model that combines both physical and behavioral healthcare services under one roof. Going into more details about the services patients can expect to receive at Spero Health, David Hayden, Senior VP of Clinical Services said, “Often times people don’t know where to turn or are afraid of judgement, and we want everyone to know that recovery is possible. Spero Health’s goal is to engage patients where they are in their journey and personalize the program to meet their specific needs so they can stabilize allowing for interventions to support sustained recovery efforts. Patients will have weekly access to a physician or nurse practitioner, counseling and recovery support services that help link them back to the community to address other issues such as housing, food insecurity, employment and much more.” About Spero Health Spero Health, Inc., is an integrated healthcare services organization specializing in local and affordable outpatient care for individuals suffering from substance use disorders with a mission to “Save Lives, Instill Hope, and Restore Relationships.” Spero Health utilizes an innovative evidence-based integrated care model that combines both physical and behavioral healthcare services under one roof to treat the whole patient. This integrated care model combines physician services (including medication-assisted treatment), behavioral health counseling, recovery support services, medication management and patient and family education. Its community-based approach to treatment allows patients to continue working and caring for their families as they overcome addiction. Based in Nashville, Tenn. and privately held by Heritage Group, Health Velocity Capital, South Central, Inc. and Frist Cressey Ventures, Spero Health operates more than 95 outpatient clinics located throughout Kentucky, Ohio, Indiana, Virginia, West Virginia and Tennessee. Spero Health is a national leader who has helped more than 35,000 patients on their journey to stable recovery from addiction and is in-network with Medicaid and most commercial insurance plans. For more information about Spero Health, please visit www.sperohealth.com Contacts Ginger Jackson Spero Health ginger.jackson@sperohealth.com(859) 209-2296

CloudBees Survey Reveals Value Stream Management Is Linchpin For Digital Transformation Success

Senior executives say VSM puts organizations ahead in digital transformation and innovation SAN JOSE, Calif.--(BUSINESS WIRE)--CloudBees, the leading software delivery platform for enterprises, today released the company’s Global Value Stream Management (VSM) Survey results revealing senior executives believe VSM is the key to an organization’s digital transformation. The survey, which polled 600 senior executives globally, also uncovers the importance of VSM in removing barriers and increasing time for innovation. In today’s digital-first landscape, organizations must digitally transform in order to remain competitive and relevant in their respective industries. Still, many digital transformation efforts fail. According to 90% of senior executives, organizations that commit to VSM will be ahead of those who do not when it comes to digital transformation, and they agree VSM makes these programs easier to achieve. The survey also reveals agreement among executives (92%) that VSM offers employees more time for innovation, alleviating time spent managing challenges. “Our global survey clearly highlights the critical role value stream management plays in the success of any organization’s digital transformation – whether they are at base camp or much further along in the journey,” said Shawn Ahmed, Chief Product Officer, CloudBees. “VSM provides visibility into every facet of end-to-end software delivery, providing vital metrics and helping to efficiently flow value – connecting software delivery to business outcomes.” Additionally, the survey uncovers significant misunderstanding about VSM – defined as a systems-thinking practice to improve the flow of business value from customer need to customer value. While 90% of senior executives in the poll say they are familiar with the concept, when questioned on the definition only half were able to select the correct answer. In fact, two in five respondents confuse the concepts of value stream management and value stream mapping. When asked about understanding of the topic within their organization, 72% admit there is still confusion about what VSM actually is and/or does. The survey also found: Business decisions around VSM are made at the C-level, according to 56% of respondents. Employee commitment to VSM is the main roadblock to adoption, with 35% of respondents saying getting mid-level employees committed to VSM thinking, and 31% saying getting senior leadership committed to VSM thinking are the biggest roadblocks. Second to this (33%) is scaling VSM efforts throughout the organization. Digital transformation plans are in place, and going well, say the majority (96%) of senior executives; only 18% say they are moving, but not fast enough. This survey was conducted among 600 senior executives – vice president and above – from companies with at least 250 employees. Respondents were evenly distributed across Australia, France, Germany, Spain, the U.K. and the U.S. Additional Resources Learn more about the CloudBees Global Executive VSM Survey Learn more about CloudBees Learn more about the CloudBees Platform About CloudBees CloudBees provides the leading software delivery platform for enterprises, enabling them to continuously innovate, compete, and win in a world powered by the digital experience. Designed for the world's largest organizations with the most complex requirements, CloudBees enables software development organizations to deliver scalable, compliant, governed, and secure software from the code a developer writes to the people who use it. The platform connects with other best of breed tools, improves the developer experience, and enables organizations to bring digital innovation to life continuously, adapt quickly, and unlock business outcomes that create market leaders and disruptors. CloudBees was founded in 2010 and is backed by Goldman Sachs, Morgan Stanley, Bridgepoint Capital, HSBC, Golub Capital, Delta-v Capital, Matrix Partners, and Lightspeed Venture Partners. Visit www.cloudbees.com and follow us on Twitter, LinkedIn, and Facebook. Contacts MediaLeeAnn Coviello PAN Communications CloudBees@pancomm.com

Luxury Menswear Retailer Harry Rosen Boosts Conversion Rates by 360% across 10,000 SKUs using Algolia

SAN FRANCISCO--(BUSINESS WIRE)--Algolia, the leading API-First Platform for Search & Discovery, announced today its collaboration with Harry Rosen, a Canadian luxury menswear retailer. Algolia‘s blazing fast product indexing capabilities coupled with powerful Search, Personalization, Dynamic Synonym Suggestions, and A/B Testing capabilities are both personalizing and dramatically transforming consumers’ experience. With Algolia, Harry Rosen has successfully built an intuitive omnichannel strategy and differentiated customer experience that is able to scale as well as streamline product discovery, resulting in a significant increase in conversions across their 10,000 products in clothing, footwear, grooming, lifestyle and accessories. “Conducting business in-store is the foundation of Harry Rosen’s business. However, with Algolia we were able to revamp our strategy to better empower online shoppers to more easily find the goods they were looking for,” said Tovi Heilbronn, Director of Digital Product and Experience at Harry Rosen. “Algolia’s solutions helped us make a seamless customer journey and helped our eCommerce strategy handle peak volumes of customers sustaining the website beyond what we thought possible.” Harry Rosen’s eCommerce website is home to 10,000 products spread across 50 categories in three distinct digital channels. This deep, broad product catalog continually challenges Harry Rosen to improve product discovery. To address these challenges, Harry Rosen deployed Algolia technology across all three of its digital channels, including HarryRosen.com, its flagship store; ShopFinalCut, the online discount option; and Herringbone, a custom internal clienteling app. Since implementing Algolia, Harry Rosen has experienced several significant growth successes, including a 360% increase in conversion rates, 68% increase in transactions and 18% increase in average order value. “Harry Rosen approached us with a vision to establish one holistic experience for their customers, whether they shop in-store or online,” said Bernadette Nixon, Chief Executive Officer for Algolia. “As Harry Rosen brings its vision to life, we are thrilled to see the impact our technology has had on its customer experience and bottom line.” In 2023, Insider Intelligence forecasts that omnichannel sales will comprise nearly 50% of all eCommerce sales. With experts anticipating a muted holiday shopping season, retailers must be diligent in avoiding website abandonment. These findings further emphasize what Harry Rosen learned in recent years: retail companies must prioritize online customer experience and recognize how relevant search drives engagement, influences buyouts and transforms the customer journey. To learn more about the Algolia tools that helped Harry Rosen boost its omnichannel strategy, read the case study here: https://resources.algolia.com/home/case-study-harryrosen. To schedule a demo of Algolia’s platform, visit algolia.com/demorequest. About Algolia Algolia is revolutionizing search and discovery by providing the world's most powerful API-First Search and Discovery Platform with its unique hybrid search engine, which is a combination of keyword and vector-based semantic search via Neuralsearch technology, in a single API. Algolia empowers both builders and business users with a better way to build unique and engaging end user experiences at Internet scale to predict what customers want with blazing fast speed and the best application browse experience leading to more remarkable Discovery. Algolia is your guide to the world’s content powering discovery where you live, work, and play. Discovery, as a result, is reinvented as the right content finds each user to inform, enrich and surprise. More than 17,000+ companies including Under Armour, Birchbox, Stripe, Slack, Medium, and Zendesk rely on Algolia to manage over 1.5 trillion search queries a year. Algolia is headquartered in San Francisco with offices in New York, Atlanta, Austin, Paris, London, Bucharest, and Sydney. To learn more, visit www.algolia.com. About Harry Rosen Harry Rosen is Canada's leading quality menswear retailer. Founded in 1954 by the man whose name the chain still bears, the eponymous store has grown from a single 500-square-foot store in Toronto to become a powerhouse in Canadian retailing with 17 stores across Canada and a robust e-commerce offering. Harry Rosen stores and its website offer extensive collections from the world's finest labels, the latest must-have designers and its very own Harry Rosen Signature brand. Whether in-store, online, via social media or at any other touchpoint, Harry Rosen is known for providing a personalized and outstanding customer experience. This trust has been gained through decades of helping men feel good and do good in their personal and professional lives. Contacts Sean Welch, PAN Communications, algolia@pancomm.com

First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)-- Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust Nasdaq Cybersecurity UCITS ETF 05.12.2022 NQCYBRN IE00BF16M727 18,550,002.00 USD 481,893,265.81 25.978 Contacts First Trust Global Funds PLC

BarrierGuard® OxygenSmart™ Recognized by the Association of Plastic Recyclers

APR formally recognizes BarrierGuard® OxygenSmart™ on meeting critical guidance for clear PET resin and molded articles MEMPHIS, Tenn.--(BUSINESS WIRE)--Ring Container Technologies, a leader in the plastic container manufacturing industry, today announced BarrierGuard® OxygenSmart™, a technology designed to protect both product freshness and the environment, has received Critical Guidance Recognition from The Association of Plastic Recyclers (APR). A program for assessing recyclability in plastic packaging design, APR's Critical Guidance Recognition is presented to companies for products that solve well-established challenges in sustainable package design. BarrierGuard® OxygenSmart™ has met the high standards for clear PET resins and molded articles, supporting the APR’s design for circularity. “While traditional barrier systems typically inhibit single stream recycling efforts, our proprietary barrier technology is the first of its kind to be formally recognized by APR as being non-detrimental to the clear PET recycling stream,” said Brian Smith, Ring Container President and Chief Operating Officer. “BarrierGuard OxygenSmart represents a significant R&D investment that took years to develop. The new technology is representative of Ring’s commitment to innovative sustainable packaging solutions.” BarrierGuard® OxygenSmart™ previously earned the How2Recycle® “Widely Recycled” label with broad acceptance in curbside programs. The barrier technology can utilize post-consumer recycled content without impacting barrier performance. “Our BarrierGuard OxygenSmart blocks or absorbs up to 30% more oxygen versus traditional barriers using 2.5 times less barrier material on average,” states Tim Ferrel, Ring Container Vice President of Business Development. “That’s cost-effective innovation our customers can relate to.” BarrierGuard® OxygenSmart™ can be customized to achieve up to a 24-month shelf life with a range of products including ketchup, other tomato-based sauces, salsas, instant coffee, nuts, and baby food among others. “APR’s Critical Guidance Recognition Program is the gold standard for determining the effect of an innovation on the quality of the plastic recycling stream,” according to Steve Alexander, APR’s President and CEO. “We commend Ring Container Technologies for the development of their BarrierGuard OxygenSmart technology, which has received Critical Guidance Recognition, a first for materials of this type.” APR is an international trade association representing the plastic recycling industry. As a member of the organization, Ring Container Technologies is committed to the success of plastic recycling. About Ring Container Technologies Ring Container Technologies is a multinational corporation headquartered in Oakland, Tennessee. Focused on developing container technology solutions for its customers for more than 50 years, the company has grown to be an industry innovation leader and one of the largest plastic container manufacturers in North America. With a commitment to be fiscally, socially, and environmentally responsible, Ring Container Technologies strives to advance innovation while exceeding expectations by design. For more information, visit www.ringcontainer.com. Contacts Beth Wilson beth@wilsonpublicrelations.com

SiTime Precision Timing Solution Provides Clocking for New AMD Alveo X3 Series Platform

Cascade ClkSoC Helps Enable Platform to Deliver Low Latency Trade Execution and Risk Management SANTA CLARA, Calif.--(BUSINESS WIRE)--#AMD--SiTime Corporation (Nasdaq: SITM), the precision timing company, announced today that AMD is using SiTime MEMS precision timing solutions for its new Alveo™ X3 series, the first AMD network cards designed with screened FPGAs and optimized specifically for low latency electronic trading. Designed for the fintech industry, AMD’s first network interface card (NIC) platform is optimized for electronic trading systems that require lower latency and security in every transaction. The SiTime SiT95145 Cascade™ clock system on a chip (ClkSoC™) is a unique single chip solution that generates all the clocks in the Alveo X3 NIC and delivers superior performance required by high-speed networks, and data centers that are the backbone of stock exchanges. “Electronic trading continues to evolve and the race to the lowest latency trade execution is critical to how financial firms operate,” said Hamid Salehi, director of product marketing, Fintech and Blockchain Technologies, AMD. “The Alveo X3 series brings low latency and adaptive computing onto a single platform to give our customers a competitive advantage for today and tomorrow. In this system, we used the SiTime SiT95145 Cascade clock system on a chip to supply all critical clocks. This precision timing device replaced multiple oscillators and resonators, simplified our clock tree design, and helped us save verification time, accelerating our time to market.” Leading financial trading firms, quants, hedge fund managers and exchanges demand near instantaneous, ultra-low-latency trade execution and risk management to maintain competitive advantage and outperform the market in today’s volatile environment. High-performance NICs built with precision timing components are critical to the speed and accuracy of automated trading systems designed to complete transactions within milliseconds. “Higher speeds and lower latency are the two major requirements of new communications networks as they enable new services,” said Piyush Sevalia, executive vice president of marketing at SiTime. “Precision timing plays a crucial role in fulfilling these requirements by delivering higher performance and robustness for modern communications deployment. SiTime has a complete portfolio of oscillators and clocks that offer compelling benefits, whether it be in performance, robustness, reliability, integration, size or power. These benefits enable unique capabilities, simplify customer’s designs, save verification time, and accelerate our customers’ time to revenue.” AMD’s FPGA-based platform delivers low-latency performance benefits through turnkey networking IP, state-of-the-art connectivity and timing technology, and hardware adaptability for evolving use cases and future electronic trading requirements. The Alveo X3 low-latency data center accelerator card can serve as a plug-and-play NIC, providing deterministic response time for rapid, reliable trade execution. Cascade, with SiTime’s MEMS technology combined with a low noise and feature-rich on-chip PLL IC, enables more robust system timing. This ClkSoC precision timing solution is designed to deliver ultra-low jitter even in the presence of noise, always-accurate frequency synthesis without crystal capacitive mismatching, 10x greater vibration resistance, always-reliable startup in harsh environments and fast hitless switching to ensure redundancy. Learn more about the SiTime precision timing solutions: Cascade Jitter Cleaners/Network Synchronizers Cascade Clock Generators Emerald Platform™ Stratum 3E OCXOs Elite Super-TCXOs® Differential Oscillators Download Alveo X3 – Cascade Clock Generator Image. Discover the full range of SiTime MEMS precision timing solutions. Read the AMD/Xilinx Alveo X3 series blog. Visit the SiTime Timing Essentials Learning Hub to learn more about precision timing. About SiTime SiTime Corporation is a market leader in silicon MEMS precision timing. Our programmable solutions offer a rich feature set that enables customers to differentiate their products with higher performance, smaller size, lower power, and better reliability. With over 3 billion devices shipped, SiTime is changing the timing industry. For more information, visit www.sitime.com. Note on Forward-Looking Statements This press release may contain forward-looking statements regarding future events. These forward-looking statements are intended to qualify for the safe harbor from liability established by the Private Securities Litigation Reform Act of 1995. Readers are cautioned that these forward-looking statements involve risks and uncertainties that could cause our actual results and the timing of events to differ materially from those anticipated in such forward-looking statements, including, but not limited to: our ability to ship products; and other risks and uncertainties described more fully in our documents filed with or furnished to the Securities and Exchange Commission. More information about these and other risks that may impact our business is set forth in our more recent Form 10-Q filed with the Securities and Exchange Commission. All forward-looking statements in this press release are based on information available to us as of the date hereof and qualified in their entirety by this cautionary statement, and we assume no obligation to revise or update these forward-looking statements. Contacts Green Flash Media for SiTime Donna St. Jean Conti pr@gflashmedia.com

Kurome Therapeutics Announces Oral and Poster Presentations on Dual IRAK1/4 Inhibitors at American Society of Hematology Annual Meeting

CINCINNATI--(BUSINESS WIRE)--#biohealth--Kurome Therapeutics, Inc., a late pre clinical stage biotech company developing novel IRAK1/4 inhibitors for oncology indications, today announced two abstracts have been accepted for oral and poster presentations at the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, to be held December 9-13, 2022, in New Orleans. The presentations highlight preclinical data supporting the importance of inhibiting both IRAK1 and IRAK4 in Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS). ASH 2022 Presentation Details: Oral Presentation Title: IRAK1 Contributes to IRAK4 Inhibitor Resistance Via Non-Canonical Signaling Mechanisms in MDS/AML Presenter and Lead Author: Josh Bennett, BS, Cincinnati Children’s Hospital Medical Center, and Daniel T. Starczynowski, PhD, Cincinnati Children’s Hospital Medical Center Session Name: Molecular Pharmacology and Drug Resistance: Myeloid Neoplasms: Immune Signaling and Antibody-therapeutic Targeting in Myeloid Neoplasms Presentation Date/Time: Monday, December 12, 2022, at 4:30 p.m. CST Location: Ernest N. Morial Convention Center, 353-355 Poster Presentation Title: Inhibition of Both IRAK1 and IRAK4 Is Required for Complete Suppression of NF-Kb Signaling across Multiple Receptor-Mediated Pathways in MDS and AML Publication Number: 2647 Authors: Jan S Rosenbaum, PhD, Kurome Therapeutics, Scott B. Hoyt, Ph.D., National Center for Advancing Translational Sciences, National Institutes of Health, Amal S. Kolt, MS, Kurome Therapeutics, Daniel A Luedtke, PhD, Kurome Therapeutics, Craig J. Thomas, PhD, National Center for Advancing Translational Sciences, National Institutes of Health, and Daniel T. Starczynowski, PhD, Cincinnati Children’s Hospital Medical Center Session Name: Molecular Pharmacology and Drug Resistance: Myeloid Neoplasms: Poster II Session Date/Time: Sunday, December 11, 2022, 6:00 - 8:00 p.m. CST Location: Ernest N. Morial Convention Center, Hall D Abstracts are available on the ASH meeting website at www.hematology.org About Kurome Therapeutics Kurome® Therapeutics is a late-stage preclinical company focused on targeting innate immune signaling pathways in cancer. Kurome is developing a series of potent IRAK1/4 and panFLT3 inhibitors that work by targeting key cancer survival pathways. The company’s first to market indications will be Acute Myeloid Leukemia (AML) and high-risk MDS. Kurome is also developing a companion diagnostic and biomarker program. Please find more information at www.kurometherapeutics.com NOTE: Daniel Starczynowks’s disclosures pertaining to Kurome Therapeutics include: Consultancy, Current holder of stock options in a privately-held company, Membership on an entity's Board of Directors or advisory committees, Patents & Royalties, Research Funding Contacts Kurome Therapeutics Mike Pistone VP, Business Development pistone@kurometx.com

ThreatConnect CEO Balaji Yelamanchili Joins TrueFort Board of Directors

Leader in Application Microsegmentation Adds Security Industry Veteran to Executive Committee WEEHAWKEN, N.J.--(BUSINESS WIRE)--#Applicationprotection--TrueFort, the application-centric microsegmentation company, today announced that Balaji Yelamanchili, CEO of threat intelligence platform provider ThreatConnect, has joined its Board of Directors. He brings more than two decades of experience to TrueFort as an operating executive and investor in high growth software companies including Symantec and Oracle. Balaji joins TrueFort CEO Sameer Malhotra, Lane Bess, Principal & Founder of Bess Ventures & Adv., Vinay Bassi, SVP/Head of FP&A and M&A at Nielsen and Karthik Subramanian, Partner at Evolution Equity Partners on the company’s board. “Balaji has served in virtually every executive role within the security industry including CEO, board member, operating executive, GM and venture partner,” said Sameer Malhotra, CEO of TrueFort. “His hands-on expertise as a chief executive, business unit leader and investor will play a pivotal role in helping TrueFort capitalize on our market opportunity and intellectual property. He is a strategic addition to our board.” “TrueFort has developed a powerful and unduplicated approach to enterprise security that views the attack surface through the lens of application behavior,” said Balaji Yelamanchili. “This allows customers to detect and prevent threats that evade many traditional security products. I look forward to working with Sameer and the rest of the Board to help TrueFort scale its business.” Prior to ThreatConnect, Balaji served as Operating Executive with Evergreen Coast Capital, the tech private equity affiliate of Elliott Management, and also as the Venture Partner at Shasta Ventures, an early stage Venture investment firm based in Silicon Valley. He previously served as Executive Vice President and General Manager of Symantec’s Enterprise Security Business Unit. Prior to Symantec, he oversaw business analytics and enterprise performance management products at Oracle as Senior Vice President. He has also held executive positions at EMC Corporation, Documentum Inc., and Rational Software, now part of IBM. Balaji holds an M.S. in Engineering from the Louisiana State University at Baton Rouge and an M.B.A. from the University of Michigan at Ann Arbor. About TrueFort TrueFort puts you in control of lateral movement across the data center and cloud. The TrueFort Cloud extends protection beyond network activity by shutting down the abuse of service accounts. Founded by former IT executives from Bank of America and Goldman Sachs, leading global enterprises trust TrueFort to deliver unmatched application environment discovery and microsegmentation for both identity and activity. For more information visit https://truefort.com and follow us on LinkedIn and Twitter. Contacts Media Contact:Marc Gendron Marc Gendron PR for TrueFort 617.877.7480 marc@mgpr.net

SecureAuth Wins 2022 Top 50 Best Workplaces of Year

IRVINE, Calif.--(BUSINESS WIRE)--#Arculix--SecureAuth, a leader in access management and authentication, today announced it has been awarded the Top 50 Best Workplaces of Year by The Silicon Review. “We are honored to receive this recognition alongside some of the best organizations in the world. With a remote-first culture and global workforce, we offer employees a unique environment to work in one of the most exciting areas of enterprise software, identity and access management, and alongside some of the most innovative minds in the industry,” said Paul Trulove, CEO of SecureAuth. Besides being one of the best places to work, SecureAuth stands out in 2022 with our latest launch of Arculix, our game-changing passwordless continuous authentication solution. It is the first line of defense to organizations to reduce the onslaught of identity attacks and the team at SecureAuth is changing how the world interacts with their increasingly digital lives.” In 2022, SecureAuth has transformed the company benefits programs for all regions to include a focus on employee wellness and mental health. The company has made it a priority to ensure that employees have the resources needed to work from home in a productive environment. Some of the changes include: Successfully developed and executed processes for virtual new hire onboarding. Leveraged the new headquarters in Irvine, CA and Buenos Aires, Argentina to organize team gatherings and activities for an enhanced work environment. These are critical for remote employees to gather and grow the employee culture. Implemented initiatives around employee engagement and development. This included driving leadership opportunities, providing employee development and training and launching an employee recognition program that fosters positive reinforcement of company values and promotes increased engagement, visibility, and productivity. Besides this great recognition, SecureAuth has also been getting a lot of accolades for technology innovation including 2022 CISO Choice Award, CyberSecurity Breakthrough Award, and Global InfoSec Award. SecureAuth will continue to reinforce its commitment to foster an inclusive and innovative work culture, that will motivate employees to deliver to the best of their abilities while feeling passionate about working at the company. About SecureAuth Corporation SecureAuth is a next-gen access management and authentication company that enables secure and passwordless continuous authentication experience for employees, partners and customers. With the only solution that can be deployed in cloud, hybrid and on-premises environments, SecureAuth manages and protects access to applications, systems and data at scale, anywhere in the world. To find out more, please visit www.secureauth.com. Follow SecureAuth via: LinkedIn: https://www.linkedin.com/company/secureauth-corporationTwitter: https://twitter.com/SecureAuthFacebook: https://www.facebook.com/SecureAuth/Blog: https://www.secureauth.com/blog/ Contacts Joan Fronske Director, Corporate Communications press@secureauth.com(925) 437-5964

SOFR Academy Welcomes Completion of PwC Review of Invesco Indexing Alignment With IOSCO Principles for Financial Benchmarks

The IOSCO Principles for Financial Benchmarks aim to create an overarching framework of Principles for Benchmarks used in financial markets. NEW YORK--(BUSINESS WIRE)--#Data--Today, SOFR Academy a digital education and market information provider welcomed the completion of an independent examination by professional services firm, PricewaterhouseCoopers LLP (“PwC”) who were appointed to perform an independent examination of Invesco Indexing indexes and a review of the group’s alignment with the International Organization of Securities Commissions’ (“IOSCO”) Principles for Financial Benchmarks. PwC assessed whether Invesco Indexing has implemented policies, processes, and control activities aligned with the IOSCO Principles. This year’s engagement represents Invesco Indexing’s first external assurance engagement and covers all Invesco Indexing’s equity, fixed income and multi-asset indexes that were published as of February 28, 2022. The review focused on Invesco Indexing’s activities implemented as at that date. Invesco Indexing LLC is an independent index provider owned by global asset management firm Invesco Ltd (NYSE: IVZ). Invesco Indexing develops and administers a wide array of equity, fixed income, multi-asset, and interest rate indexes. These indexes represent a full range of strategies reflecting both local and global markets. Invesco Indexing was also one of the first third-country benchmark administrators to be approved under the EU Benchmarks Regulation and, since January 2021, the UK Benchmarks Regulation. “Since its founding in 2017, Invesco Indexing has developed and maintained the highest standards of governance and control of its financial benchmarks,” noted Scott Wolle, CFA, Head of Systematic and Factor Investing at Invesco. “We are delighted with the conclusions of the independent examination, which reflect our commitment to industry best practices and our alignment with the IOSCO Principles.” On July 12, 2022, Invesco Indexing launched the first-of-their-kind USD Across-the-Curve Credit Spread Indices (“AXI”) and USD Financial Conditions Credit Spread Indices (“FXI”). These indices work in conjunction with the Secured Overnight Financing Rate (“SOFR”) and address concerns communicated by a group of American banks that under a SOFR-only environment in times of economic stress, the return on banks’ SOFR-linked loans would decline, while banks’ unhedged costs of funds would increase, thus creating a significant mismatch between bank assets (loans) and liabilities (borrowings). AXI and FXI were not included in this initial independent examination. “IOSCO’s work helps to protect investors, ensure market integrity, and support global financial stability – their work is more important than ever,” said Marcus Burnett, CEO of SOFR Academy. “The IOSCO Principles represent the highest possible standards for the maintenance and governance of financial benchmarks. We are pleased that Invesco appointed PwC to complete this thorough and independent review and we welcome the report results,” added Burnett. “The results of this independent examination confirm Invesco Indexing’s serious commitment to transparency and adherence to strict governance processes,” added Caitlen Laue, Director of Operations for Invesco Indexing. The full scope of indexes covered by the review, including PwC’s assurance report, is included within the report which can be accessed here. If you have any questions, please contact IndexSupport@invesco.com. Additionally, full details of Invesco Indexing’s methodology documents are available here. About SOFR Academy SOFR Academy is a member of the Asia Pacific Loan Market Association (APLMA), American Economic Association (AEA), the Loan Syndications and Trading Association (LSTA), the International Swaps and Derivatives Association (ISDA), the Bankers Association for Finance and Trade (BAFT) which is a wholly owned subsidiary of the American Bankers Association (ABA), the U.S. Chamber of Commerce (USCC) and Bretton Wood Committee (BWC). For more information, please visit www.SOFR.org. Invesco Disclosures The information provided is for informational purposes only and should not be construed as an offer to buy or sell any financial instruments, or a recommendation for any security or fund interest. Invesco Indexing LLC is not an investment adviser or fiduciary and makes no representation regarding the advisability of investing in any security or strategy. There can be no assurance that an investment strategy based on the Invesco Indexes will be successful. Indexes under administration by Invesco Indexing LLC are not individually certified as being IOSCO compliant. Indexes are unmanaged and it is not possible to invest directly in an index. Exposure to an asset class or trading strategy represented by an index is only available through investable instruments (if any) based on that index. Invesco Indexing LLC does not issue, sponsor, endorse, market, offer, review, or otherwise express any opinion regarding any fund, derivative or other security, financial product or trading strategy that is based on, linked to, or seeks to track the performance of any Invesco Indexing LLC. Invesco Indexing LLC is an indirect, wholly owned subsidiary of Invesco Ltd. SOFR Academy Disclosures SOFR Academy supports SOFR, and near risk-free rates. Over time, we also support robustly defined across-the-curve credit spread supplements such as AXI and FXI which can be used in conjunction with risk-free rates. SOFR is published by the Federal Reserve Bank of New York (The New York Fed) and is used subject to The New York Fed Terms of Use for Select Rate Data. The New York Fed has no liability for your use of the data. AXI is not associated with, or endorsed or sponsored by, The New York Fed, or the Federal Reserve System. Darrell Duffie, The Adams Distinguished Professor of Management and Professor of Finance at Stanford Graduate School of Business, is a co-author of the proposal for AXI, but has no related compensation or other affiliation with its commercialization. Contacts SOFR Academy Jorge Cosano-Martinez press@SOFR.orgTel: +1 855 236 6106

ICR ESG Advisory & Shareholder Activism Team Announces Stellar Year

Advises more than 30 clients on strategic ESG and shareholder advisory solutions Expert-led team drives transparent disclosures across all industries and successfully helps companies win proxy battles Team recently expanded to provide Private Equity ESG due diligence services NEW YORK--(BUSINESS WIRE)--ICR, a global leader in strategic communications, today announced that it advised more than 30 companies on environmental, social, and governance (ESG) and shareholder activism solutions in 2022. Services included ESG strategy development, report creation, shareholder engagements, and activism defense. In its advisory capacity, ICR’s ESG Advisory & Shareholder Activism team provides independent and objective counsel to private and public companies, as well as private equity firms across all industry groups, including energy, healthcare, consumer discretionary, and financials. “ICR’s ESG Advisory & Shareholder Activism team has grown significantly since it was established in 2020, differentiated by their experience working in senior stewardship roles at the world’s largest passive investment firms as well as their ability to collaborate with ICR’s 20+ industry-focused Investor Relations teams,” said Tom Ryan, CEO of ICR. “This has enabled them to provide clients with the tools and resources to approach complex issues in an authentic and deliberate way. By advising on strategy, disclosure, and engagement, our team delivers a holistic suite of services at the exact time the market desperately needs clarity and direction. During 2022 we engaged with more than twice the number of companies than in 2020, underscoring a leading position in ESG advisory and shareholder activism solutions.” The ICR approach brings a differentiated single-continuum advisory service to the marketplace, combining strategic ESG advisory and activist defense services with direct shareholder engagement. This addresses event-driven issues and proactively supports good corporate reporting. In collaboration with ICR Branding + Creative, ICR delivers an end-to-end reporting solution from conception and development to design and production that uniquely delivers a company’s ESG story. ICR’s ESG Advisory & Shareholder Activism team is on track to deliver more than 20 ESG reports in 2022, including reports for Alignment Health, Spartan Nash, and Leslie’s Pool. The team achieved notable engagement successes in 2022 with positive client outcomes on climate- and governance-related shareholder activism. In addition, the team grew its PE due diligence services, securing strong ongoing business relationships for target company ESG analysis. “Building on the significant momentum in our business this past year, we are confident that we will continue to deliver exceptional and unparalleled service to our clients across the ESG and shareholder activism landscape in the coming years,” said Lyndon Park, Managing Partner of ESG Advisory and Shareholder Activism. About ICR Established in 1998, ICR partners with its clients to execute strategic communications and advisory programs that achieve business goals, build awareness and credibility, and enhance long-term enterprise value. The firm’s highly-differentiated service model, which pairs capital markets veterans with senior communications professionals, brings deep sector knowledge and relationships to approximately 1,000 clients across more than 20 industry groups. ICR’s healthcare practice operates under the Westwicke brand (www.westwicke.com). Today, ICR is one of the largest and most experienced independent communications and advisory firms in North America, maintaining offices in New York, Norwalk, Boston, Baltimore and Beijing. Learn more at www.icrinc.com. Follow us on Twitter at @ICRPR. Contacts Media:Brian Ruby Brian.ruby@icrinc.com(203) 682-8268

First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)-- Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust US Large Cap Core AlphaDEX UCITS ETF 05.12.2022 FEX IE00B8X9NW27 788,469.00 USD 52,391,236.60 66.447 Contacts First Trust Global Funds PLC

First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)-- Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust NYSE Arca Biotechnology UCITS ETF 05.12.2022 FBTU.LN IE00BL0L0H60 350,002.00 USD 6,660,533.43 19.030 Contacts First Trust Global Funds PLC

United States Healthcare Market 2022 to 2026: Featuring Health Care Cost Institute, Kaiser Family Foundation and Health Insurance Marketplace Among Ot

DUBLIN--(BUSINESS WIRE)--The "United States Healthcare Market 2022-2026" report has been added to ResearchAndMarkets.com's offering. This report forecasts to 2022 and 2026 US healthcare expenditures in nominal and real (inflation-adjusted) US dollars. Total nominal expenditures are segmented by type in terms of: hospital; physician and clinical; dental; other professional providers (e.g., chiropractors, speech therapists); nursing and continuing care retirement facilities; home healthcare; other providers, such as assisted living facilities, community centers, and residential intellectual and developmental disability facilities; prescription drug retail sales; other medical product retail sales, such as disposable medical supplies, durable medical equipment, and non-prescription drugs; and nonpersonal healthcare expenditures, such as net cost of private healthcare insurance, medical structures and equipment, and public health activities. Total nominal expenditures are also segmented by funding source as follows: private insurance; Medicare; Medicaid; out-of-pocket; investment; and other funding sources such as veteran's insurance programs, public welfare programs, and public health activities. To illustrate historical trends, total healthcare expenditures in nominal and real terms, and the various segments in nominal terms, are provided in annual series from 2011 to 2021. Key macroeconomic indicators are also provided with quantified trends. Other various topics, including profiles of pertinent leading companies, are covered in this report. Key Topics Covered: 1 MARKET ENVIRONMENT Historical Trends Key Economic Indicators Medical Services Expenditures by Disease Regulatory Factors 2 EXPENDITURE SEGMENTATION & FORECASTS Hospital Physician & Clinical Dental Other Professional Providers Nursing & Continuing Care Retirement Facilities Home Healthcare Other Providers Medical Products Retail Sales Nonpersonal 3 FUNDING SEGMENTATION & FORECASTS Private Insurance Medicare Medicaid Out-of-Pocket Investment Other Sources 4 INDUSTRY STRUCTURE Industry Characteristics Market Share 5 ABOUT THIS REPORT Companies Mentioned ABIM Foundation American Dental Association American Hospital Association American Medical Association America's Essential Hospitals America's Health Insurance Plans Congressional Budget Office Federation of American Hospitals Health Care Cost Institute Kaiser Family Foundation United States Census Bureau United States Department of Defense Military Health System TRICARE United States Department of Health & Human Services Agency for Healthcare Research and Quality Centers for Disease Control and Prevention National Center for Health Statistics Centers for Medicare & Medicaid Services Health Insurance Marketplace Medicaid.gov Medicare.gov Quality Payment Program Health Resources & Services Administration Indian Health Service US Preventive Services Task Force United States Department of Veterans Affairs Veterans Health Administration For more information about this report visit https://www.researchandmarkets.com/r/366m0a Contacts ResearchAndMarkets.com Laura Wood, Senior Press Manager press@researchandmarkets.comFor E.S.T Office Hours Call 1-917-300-0470 For U.S./ CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900

Seniors Get Ultimate Gift at Surprise Holiday Party with over 25,000 Lights, Musicians, and Hundreds of Visitors

Klick Health produces ‘Light The Way’ holiday video with long-term care home to help minimize loneliness among seniors during the holidays TORONTO & NEW YORK--(BUSINESS WIRE)--The holiday season can be a lonely time for many seniors–increasingly so since the start of the pandemic–so Klick Health today released its ‘Light The Way’ holiday video to encourage people to “be the light in someone’s day.” The sentimental three-minute holiday production was created in partnership with the Tony Stacey Centre for Veterans Care (TSCVC) and shines a spotlight on the power of community and connection. Set to original, new music by singer/songwriter Taylor Ashton, ‘Light The Way’ provides a heartwarming glimpse inside the non-profit long-term care home as Klicksters work outside to surprise residents with a larger-than-life holiday celebration. In the video, hundreds of family, friends, Klicksters, and community members turn up in droves for the event, featuring over 25,000 lights, a giant Santa throne and other festive decor, live entertainment, and hot cocoa. “We are grateful to everyone at the Tony Stacey Centre for collaborating with us to bring to life such an important story,” said Chief Creative Officer Rich Levy. “Making this video has been a labor of love that has brought together the expertise of so many Klick crafts–from creative and production, to medical, events & experience, and more–all to bring joy and togetherness to an often overlooked community.” According to the TSCVC, 75 percent of its residents don’t receive any visitors during the holiday season. Recently published research in the Journal of the American Heart Association found that social isolation and loneliness increase the risk of heart attack, stroke, or death by 30 percent. For many seniors, the ongoing COVID-19 pandemic has only made loneliness worse, and the holidays can be an especially difficult time. Raising funds and awareness for long-term care homes Klick’s Chief People Officer Glenn Zujew said, “We’ve been creating annual holiday videos to help spread festive cheer and give back to communities for over a decade, but this one is extra special. There’s a beautiful and tender emotionality to ‘Light The Way’ that we hope resonates around the world, and reminds everyone that human connection is the ultimate holiday gift.” ‘Light The Way’ also supports TSCVC’s ongoing fundraising efforts, with Klick donating $1 for each of the video’s first 10,000 YouTube views to the Toronto long-term care home, which has launched a fundraising campaign to redevelop its aging building. The company is also supporting a New Jersey-based long-term care home, sending homemade holiday cards to its residents and adding the care residence to its internal Klick it Forward charitable giving platform for the month of December, so Klicksters can direct the donation dollars they receive there. In past years, Klick’s holiday videos have inspired millions of people with themes of kindness, empathy, and creativity. Last year, the company gave hundreds of its team members each a $100 bill with the simple directive to use it to ‘Spread Joy.’ Its popular 2020 ‘When Nobody’s Watching’ animated video received almost five million YouTube views, while its 2019 ‘Kindness is Contagious’ production received six million views and won a Webby Award. In 2019, the CW Network featured Klick’s ‘Epic Office Holiday Remix with Andrew Huang’ on its ‘Greatest Holiday Commercials Countdown’ show. Klick’s ‘Light The Way’ holiday video can be viewed, liked, and shared on YouTube at https://www.youtube.com/watch?v=hjoytc_KoMQ. About Klick Health Klick Health is the world’s largest independent commercialization partner for life sciences. For over 25 years, Klick has been laser-focused on developing, launching, and supporting life sciences brands to maximize their full market potential as a core commercialization partner. Klick recently ranked #1 on Medical Marketing + Media (MM+M) magazine’s Agency 100 list for the fifth straight year and was named an MM+M Large Agency of the Year for both 2020 and 2021, marking 10 Agency of the Year industry awards in 11 years. Follow Klick Health on LinkedIn and for more information on joining Klick, go to careers.klick.com. About Klick Group The Klick Group of companies–Klick Health (including Klick Katalyst), Klick Media Group, Klick Applied Sciences (including Klick Labs), Klick Consulting, Klick Ventures, and Sensei Labs–is an ecosystem of brilliant talent collectively working to maximize their people’s and clients’ full potential. Established in 1997, Klick has teams across North America, with offices in New York, Philadelphia, and Toronto, and is opening global offices in Basel, Buenos Aires, London, Munich, Paris, Singapore, São Paulo, and Tokyo. Klick has consistently been named a Best Managed Company and Great Place to Work. In 2021, the company was recognized with 15 Best Workplace awards, including Best Workplaces for Women, Best Workplaces for Inclusion, Best Workplaces for Giving Back, Fast Company’s Best Workplaces for Innovators, and FORTUNE’s Best Workplaces for Millennials. Contacts For media inquiries:Marisa McWilliams, Senior Manager, Communications, Klick Health Email: pr@klick.comPhone: 862-335-8165 Amanda Ferguson, Manager, Communications, Klick Health Email: pr@klick.comPhone: 416-214-4977

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